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The effect of environmental stress on ageing in a termite species with low social complexity

by Ageing and Longevity | Mar 29, 2021 | Uncategorized

Fascinatingly, sociality in invertebrates is associated with longevity and plasticity of the pace of ageing. To reveal more about this phenomenon, Rau and colleges looked at how non-reproducing and reproducing termites responded to environmental stress in the form of... Read More

Gut microbiome pattern reflects healthy ageing and predicts survival in humans

by Ageing and Longevity | Mar 29, 2021 | Uncategorized

A team in America analysing gut microbiome outputs in blood samples found evidence for a potential link between ageing patterns and microbiome composition in the gut. They identified that healthy ageing in individuals could be partly predicted by a depletion of core... Read More

Intermittent and periodic fasting, longevity and disease

by Ageing and Longevity | Mar 6, 2021 | Uncategorized

We have all heard of the benefits of intermittent fasting and longevity. In this review, Longo and colleagues discuss the latest cellular and organismal literature involving intermittent and periodic fasting, and their effect on ageing. Intermittent fasting is defined... Read More

Recruitment of inflammatory monocytes by senescent fibroblasts inhibits antigen-specific tissue immunity during human aging

by Ageing and Longevity | Mar 6, 2021 | Uncategorized

As most will know, senescent cells lead to a plethora of ageing-related pathophysiologies. In this recent study, Chambers et al. describe how cutaneous senescent fibroblasts are responsible for the non-specific immune response to injection of varicella zoster virus... Read More

The transcriptional coactivator CBP/p300 is an evolutionarily conserved node that promotes longevity in response to mitochondrial stress

by Ageing and Longevity | Mar 6, 2021 | Uncategorized

In this elegant study, Li and colleagues show how the mitochondrial unfolded protein response (UPRmt) can promote longevity in Caenorhabditis elegans. Using a focused RNAi screen, the authors discover that CREB-binding protein 1 (CBP-1) is a crucial mediator of the... Read More
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