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SUMMARY:The Founding Father of Genetics\, Prof. George Church: on Gene Therapy and Longevity
DESCRIPTION:The Oxford Society of Ageing and Longevity is delighted to invite you to a captivating online event featuring Dr. George Church\, a visionary scientist and pioneer in the fields of genetics\, synthetic biology\, and gene therapy. A professor at both Harvard Medical School and MIT\, Dr. Church consistently pushes the boundaries of scientific understanding\, opening new possibilities for the future of human health and longevity. \nJoin us Wednesday\, May 3rd. 7:00pm UK time\, online\, to explore the forefront of longevity research and the transformative potential of gene therapy in extending a healthy human lifespan. Dr. Church’s innovative contributions to genomic science include the development and optimisation of CRISPR-Cas9\, a ground-breaking gene-editing technology that has revolutionized our ability to modify DNA with unparalleled precision. This revolutionary tool has not only deepened our understanding of genetic mechanisms but also paved the way for new treatments for genetic disorders and personalized medicine. \nHis recent work has focused on gene therapy for promoting health and extending lifespan. The first study\, “A single combination gene therapy treats multiple age-related diseases\,” published in 2019\, investigates the potential of a single combination gene therapy to address multiple age-related diseases simultaneously. Using adeno-associated virus (AAV) vectors to deliver a combination of three longevity-associated genes in mice models\, the\nresearchers observed significant improvements in various age-related diseases\, such as heart and kidney diseases\, obesity\, and cognitive decline. \nThe second study\, “New intranasal and injectable gene therapy for healthy life extension\,” published in 2022\, focuses on developing innovative gene therapy approaches to promote healthy life extension. The research explores the use of intranasal and injectable gene therapies to target cellular mechanisms associated with aging. The study demonstrates the potential of these novel therapies for promoting health and longevity in humans. \nIn the realm of synthetic biology\, Dr. Church has co-developed Multiplex Automated Genome Engineering (MAGE)\, a method for large-scale\, targeted manipulation of cellular genomes. This transformative technology has led to breakthroughs in environmental sustainability\, such as engineering microbes to produce biofuels and sequester carbon dioxide\, providing innovative solutions to some of the world's most pressing questions. As an advocate for open science\, Dr. Church launched the Personal Genome Project\, an ambitious initiative aimed at creating a public repository of human genomes and medical histories. This pioneering project seeks to accelerate the advancement of personalized medicine by making vital genetic data available to researchers worldwide. \nDr. Church’s research also delves into combating pathogens using novel approaches\, such as phage-assisted continuous evolution (PACE). His work in this area holds the potential to revolutionize the way we fight infectious diseases and tackle antibiotic resistance\, showcasing the transformative power of his scientific contributions. In addition to his numerous accomplishments\, Dr. Church is a captivating speaker known for his ability to inspire audiences with his visionary ideas and dedication to pushing the frontiers of science. \nYou are encouraged to pre-submit your questions for by emailing ageingandlongevity@gmail.com. There will be a live Q&A session during the event\, where you can ask your questions and engage in stimulating discussions with Dr. Church. \nWe look forward to welcoming you to this online event\, as we explore the fascinating world of gene therapy\, synthetic biology\, and their potential contributions to human longevity. \nRegister now to secure your spot! \nAll the best\,\nThe OSAL Committee \nWith special thanks to Marina Cerezuela\, DPhil candidate in gene therapy\, for development of the introductory text.
URL:https://www.ageingandlongevity.org/event/the-founding-father-of-genetics-prof-george-church-on-gene-therapy-and-longevity/
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SUMMARY:Decoding Aging in Dogs (and Humans!)\, with Dr. Matt Kaeberlein
DESCRIPTION:Decoding Longevity: Dogs\, Humans\, and the Shared Journey of Aging with Dr. Matt Kaeberlein \nThe Oxford Society of Ageing and Longevity is pleased to invite you to an exciting virtual event featuring Dr. Matt Kaeberlein\, a leading researcher in the field of aging. As a Professor at the University of Washington (UW) School of Medicine and the Chief Science Officer at Optispan Ventures\, Dr. Kaeberlein is dedicated to studying and understanding biological aging and how we can enhance our health as we age. \nMark your calendars for Thursday\, May 25th at 7:30 pm UK time\, as we embark on an exciting journey to the frontier of aging research. Dr. Kaeberlein’s groundbreaking work provides a fresh perspective on how we view aging\, shifting the focus from lifespan to healthspan – the period of life spent in good health. \nThe talk will focus on his flagship Dog Aging project\, where Kaeberlein is seeking to unlock the secrets of longer\, healthier lives for our canine companions. In doing so\, him and his team are fielding opportunities to translate outcomes to humans – adding a new definition to ‘mans best friend’. \nDr. Kaeberlein is co-founder and co-director of the pioneering Dog Aging Project. His unique approach of studying our canine companions brings a whole new dimension to the field. This project illuminates the common biological threads of aging across species\, and importantly\, identifies interventions that could promote healthspan in both dogs and humans! \nDr. Kaeberlein’s research covers a wide range of topics\, from the effects of caloric and protein restriction to the potential health benefits of substances like rapamycin. His work helps us understand the complex interactions between genetics and the environment in the aging process. \nWe invite you to pre-submit your questions for Dr. Kaeberlein by emailing ageingandlongevity@gmail.com. There will also be a live Q&A session that will provide you with the opportunity to further engage with him during the event. \nJoin us in this exciting session as we explore the future of healthspan\, aging\, and longevity. \nDon’t miss this opportunity – register today to secure your spot!
URL:https://www.ageingandlongevity.org/event/decoding-aging-in-dogs-and-humans-with-dr-matt-kaeberlein/
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